Pioneer Access is DNA ME's closed beta for researchers. Native methylation — 5mC, 5hmC, 6mA — read directly from the nanopore signal, alongside genetic variants, in a single run. No bisulfite. No GPUs. No bioinformatics team. Send samples to our Hamburg lab; receive publication-ready data in 48–96 hours.
Genetics and epigenetics in a single nanopore run. No GPU infrastructure. Oxford Nanopore technology with proprietary reagents and software — built in-house because off-the-shelf wasn't good enough.
Match your question to the right analysis depth: targeted methylation and variants with Hybridisation Capture (HBs), full native epigenetics — 5mC, 5hmC, 6mA — with CRISPR Capture (CBs), or exome-wide discovery with WES G2 when you don't yet know where to look. Digital panels mean no new chemistry for a new target.
Package and ship to our Hamburg lab using standard protocols. We confirm receipt within 4 hours and begin processing immediately. Ambient or cold-chain — we handle both.
Publication-ready data, quality metrics, and methods-section language — all delivered in 48–96 hours, tier-dependent. We did it again. And again. That's the point.
Match the analysis depth to your question — from targeted enrichment to exome-wide discovery, all on the same nanopore platform.
Targeted 5mC methylation and genetic variants. Bait-based enrichment, up to 24 samples per flow cell. Entry tier. Turnaround 48–96 h.
Full native epigenetics: 5mC + 5hmC + 6mA. CRISPR/Cas9-guided, long reads (5–20 kb) for allele-specific and haplotype-resolved methylation. Turnaround 60–96 h.
Exome-wide full native epigenetics via adaptive sampling, no physical enrichment. For discovery, when you don't yet know where to look. Turnaround 72–96 h.
Pioneer Access is not a discounted trial. It is a structured collaboration — you bring the research, we bring the speed, the flexibility, and the scientific support.
Your first three samples processed at no charge. Evaluate the quality, the turnaround, and the data before committing any project budget.
Pioneer participants are prioritised in the processing queue.
A dedicated channel to DNA ME's lab scientists. Not a ticketing system — a direct line for troubleshooting, protocol optimization, and scientific dialogue.
Contribute data and feedback. Earn co-authorship on DNA ME's validation paper. A concrete publication for your CV — with minimal additional effort.
Need a panel we don't have yet? Your request goes to the front of the development queue. Your targets become available panels.
Permanent recognition as a DNA ME Founding Researcher. Digital badge, website listing, and priority invitations to all future DNA ME events.
Methods-section language, supplementary data formatting, and quality metrics documentation — so your results go straight into your manuscript.
Commit to 25+ samples and receive quarterly invoicing instead of per-sample billing. Less admin, more research.
Pioneer Access welcomes researchers from any DNA-based research discipline. We have reserved spots across our five priority verticals — and one open spot for exceptional applications from any field.
Gut, oral, skin, soil, marine communities
Pathogen ID, genetic screening, breed verification
Fish, amphibians, invertebrates, water quality
Plant pathogens, SNP genotyping, GMO detection
Pathogens, species auth, allergen detection
Also open to: oncology, epigenetics, pharmacogenomics, forensics, infectious disease, ancient DNA, conservation genetics, rare disease, CRISPR validation, and more. Particularly suited to studies where methylation matters — imprinting, epigenetic clocks, ctDNA methylation, microbial 6mA.
Pioneer Access is for researchers at recognized institutions conducting DNA-based research. We review applications on a rolling basis.
DNA ME operates under Research Use Only (RUO) designation. All results are for research purposes only.
Admission is ongoing — there are no deadlines. Rolling review, with a decision within five business days. Takes about 10 minutes to complete.